Foundation / Corporation
Alex’s Lemonade Stand Foundation (ALSF)
09/30/19 11:59 PM ET
Grants to USA, Canada, and International faculty at nonprofit research organizations and institutions to gather research data on childhood and adolescent cancer. Funding is intended to create sets of single-cell resolution profiling data. In-kind data lab services and consultations are also available.
Alex’s Lemonade Stand Foundation seeks to create datasets that profile pediatric cancers at a single-cell resolution level. Single-cell profiling can provide insights into the heterogeneity of cells in a tumor and the surrounding tumor microenvironment, as well as variability in the states of cancer cells, all of which can influence the cancer’s response to treatments. The pediatric cancer atlas will be an open resource for discovery, and a primary goal of this effort is to produce data that can be harmonized. The Single-cell Pediatric Cancer Atlas (ScPCA) will fund the profiling of pediatric cancer samples. This award is designed to produce an atlas of gene expression profiles for pediatric cancers of different types and from different organ sites that can be harmonized to allow comparison within and across type and site.
Data sharing is a critical component of the application, and applicants are expected to share the resulting raw and processed data. For more details about this requirement, see https://www.alexslemonade.org/sites/default/files/single-cell_pediatric_cancer_atlas_rfa.pdf#page=5.
In addition to the full requested budget, applicants may elect to use the ALSF Childhood Cancer Data Lab (CCDL) for the quantification step of single-cell and/or bulk gene expression analysis. The CCDL can also be used for the analysis portion of expression analysis, but applicants should first discuss planned applications with the CCDL and request a letter of support so that adequate support will be available. The CCDL is also available for consultations regarding the management and sharing of the research data which is a required element of this award.
GrantWatch ID#: 186756
The requested budget should be in proportion to the scope of the proposed project and should be at or under $200k USD in direct costs over one year.
Projected Start Date: January-March 2020
Grant Duration: 12 months
Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.
Apply online: https://alsfapps.force.com/FGM_Portal__CommunitySignin
For questions regarding this grant mechanism, reach out to Anna Greene, Director of Science, at 866-333-1213 or by email at firstname.lastname@example.org.
For applicants interested in using the CCDL for gene expression analysis, reach out to the CCDL Director, Casey Greene, PhD, at email@example.com to discuss the research plan in more detail.
Alex’s Lemonade Stand Foundation
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