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BETO Scale-up and Conversion

Grants to USA Nonprofits, For-Profits, Agencies, Educational Institutions,
and Individuals for Research Related to Renewable and Clean Energy

Agency Type:


Funding Source:

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U.S. Department of Energy (DOE) - Office of Energy Efficiency and Renewable Energy (EERE)

Conf. Date:


LOI Date:


Deadline Date:

06/21/21 5:00 PM ET


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Cooperative agreements to USA and territories nonprofit and for-profit entities, government entities, tribal governments, educational institutions, and individuals for research and development projects that address the climate crisis. Applicants must submit a concept paper before submitting a proposal. Required registrations may take several weeks to complete.

The Bioenergy Technologies Office (BETO) is focused on developing technologies that convert domestic biomass and other waste resources (e.g., municipal solid waste, biosolids) into low-carbon biofuels and bioproducts. These bioenergy technologies can enable a transition to a clean energy economy, create high-quality jobs, support rural economies, and spur innovation in renewable energy and chemicals production – the bioeconomy. The activities funded through this opportunity will mobilize public clean energy investment in the biofuels, chemical and agricultural industries, accelerate the deployment of bioenergy technologies, and support achieving economy-wide net-zero emissions by 2050.

This FOA supports high-impact technology RDD&D to accelerate the bioeconomy and, in particular, the production of low-carbon fuels for the aviation industry. BETO is focusing on applied RDD&D to improve the performance and reduce cost of biofuel production technologies and scale-up production systems in partnership with industry. By reducing cost and technical risk, BETO can help pave the way for industry to deploy commercial-scale integrated biorefineries and reduce greenhouse gas emissions from hard to decarbonize sectors, such as aviation. The Program is focused on developing and demonstrating technologies that are capable of producing low-carbon drop-in biofuels at $2.50 per gallon gasoline equivalent (GGE) by 2030, as well as associated renewable chemical co-products to achieve this target.[2] BETO is focused on biofuel production pathways that can deliver at least 70% lower lifecycle greenhouse gas emissions than petroleum.

The research and development (R&D) activities to be funded under this FOA will support the government-wide approach to the climate crisis by driving the innovation that can lead to the deployment of clean energy technologies, which are critical for climate protection. Specifically, this FOA will support high-impact RDD&D focusing on the production of low-GHG fuels for the aviation industry, as well as the long-haul trucking and marine industries by soliciting proposals to scale-up technologies; cost effectively produce biomass derived sugars as an intermediate for the production of biofuels and bioproducts; and support cost effective separation technologies. In addition, the FOA will support increasing the efficiency of residential wood heaters and the production of renewable natural gas.

Topic Areas:

  1. Scale-up of Biotechnologies
    • 1a: Pre-Pilot for Biofuels and Bioproducts
    • 1b: Pilot for Biofuels and Bioproducts
    • 1c: Demonstration for Biofuels and Bioproducts
  2. Affordable, Clean Cellulosic Sugars for High Yield Conversion
  3. Separations to Enable Biomass Conversion
    • 3a: Separations to Improve Arrested Anaerobic Digestion Process Development
    • 3b: Separations to Enable Biomass Conversion (Bioprocessing Separations Consortium)
  4. Residential Wood Heaters
  5. Renewable Natural Gas (RNG)
    •  5a: RNG Research & Development
    •  5b: RNG Pilot

GrantWatch ID#:

GrantWatch ID#: 195533

Estimated Total Program Funding:


Number of Grants:

EERE anticipates making approximately 11 to 27 awards under this FOA. EERE may issue one, multiple, or no awards.

Estimated Size of Grant:

Individual awards may vary between $500,000 and $5,000,000 for FY21 selected projects across all Topic Areas. For more information about award sizes for topic areas, see table in Section II.A.ii. in the FOA in Supporting Documents below.

Term of Contract:

EERE anticipates making awards that will run from 12 months up to 60 months in length, comprised of one or more budget periods (see table in Section II.A.ii. in the FOA document in Supporting Documents below for topic area and subtopic area estimated lengths).


  • City or township governments
  • County governments
  • For profit organizations other than small businesses
  • Independent school districts
  • Indian housing authorities
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities
  • See RFP and/or Grant Guidelines for full eligibility
  • Small businesses
  • Special district governments
  • State governments
  • Individuals

Additional Eligibility Criteria:

The eligibility requirements for Topic Area 2, “Affordable, Clean Cellulosic Sugars for High Yield Conversion” are different from those of Topic Areas 1 and 3-5, which are subject to the eligibility criteria set forth below. DOE/NNSA Federally Funded Research and Development Centers (FFRDCs) are eligible to apply for funding as a prime recipient or subrecipient under Topic Area 2 only. In all other topic areas and subtopic areas (1a, 1b, 1c, 3a, 3b, 4, 5a, and 5b) DOE/NNSA and non-DOE/NNSA FFRDCs are restricted from applying for funding as a Prime Recipient, but are eligible to participate as a Subrecipient. Each FFRDC is permitted to participate as a Subrecipient with effort equivalent to up to 50% of the total estimated cost of the project; however, in aggregate, total FFRDC effort shall not exceed 50% of the total estimated cost of the project.

Pre-proposal Conference:

An informational webinar will be held on April 16th, 2021 at 3:00 PM ET. The webinar will review the Funding Opportunity Announcement and Merit Review process, but will only discuss Topic Area 1: Scale-up of Biotechnologies specific requirements due to the complex nature of the topic area. Please note, there are no particular advantages or disadvantages to the application evaluation process with respect to participating in the webinar. Your participation is completely voluntary. Please register for the webinar at:

Pre-Application Information:

- Concept Paper Submission Deadline: 4/30/2021 5:00 PM ET
- Full Application Submission Deadline: 6/21/2021 5:00 PM ET
- View Full Application Reviewer Comments Period: 7/16/2021 5:00 PM ET – 7/20/2021 5:00 PM ET

The application process will include two phases: A Concept Paper phase and a Full Application phase. Only applicants who have submitted an eligible Concept Paper will be eligible to submit a Full Application.

Applicants are strongly encouraged to submit their Concept Papers, Full Applications, and Replies to Reviewer Comments at least 48 hours in advance of the submission deadline.

EERE will accept only new applications under this FOA. EERE will not consider applications for renewals of existing EERE-funded awards through this FOA.

Cost Sharing:
- Topic Areas 1a, 2, 3a, 3b, 4, and 5a: The cost share must be at least 20% of the total allowable costs for research and development projects.
- Topic Area 1b, 1c, and 5b: The cost share must be at least 50% of the total allowable costs for demonstration projects.
For more information, see pages 64 and 131 of the FOA document in Supporting Documents below.

There are several one-time actions before submitting an application in response to this FOA, and it is vital that applicants address these items as soon as possible. Some may take several weeks, and failure to complete them could interfere with an applicant’s ability to apply to this FOA, or to meet the negotiation deadlines and receive an award if the application is selected. These requirements are as follows:
1. EERE Exchange: Register and create an account on EERE Exchange at
2. DUNS Number: Obtain a DUNS number (including the plus 4 extension, if applicable) at
3. System for Award Management: Register with the SAM at
4. FedConnect: Register in FedConnect at
5. Register in ( to receive automatic updates when Amendments to this FOA are posted. However, please note that Concept Papers and Full Applications will not be accepted through

Required Application Documents:

View this opportunity on

FOA Webinar Recording:

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Submit applications at

Questions regarding the FOA must be submitted to

Applicants that experience issues with submission PRIOR to the FOA deadline: In the event that an applicant experiences technical difficulties with a submission, the applicant should contact the EERE Exchange helpdesk for assistance ( The EERE Exchange helpdesk and/or the EERE Exchange system administrators will assist applicants in resolving issues.

CFDA Number:


Funding or Pin Number:

FOA DE-FOA-0002396

URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

USA Territories: American Samoa (USA)   Guam (USA)   Puerto Rico (USA)   Virgin Islands (USA)   Northern Mariana Islands (USA)

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